Objective and comprehensive evidence regarding the effects of music for anxiety reduction is necessary to promote research advancement and best clinical practices in music therapy. The aim of this study is to meta-analyze the effect of music interventions conducted by music therapists on anxiety and to compare the differences in effect size when accounting for variables such as sample size, participant characteristics, anxiety type, and interventions characteristics. A total of 33 experimental studies, which met inclusion criteria, were extracted from online databases, such as Research Information Sharing Service(RISS). Followed by data-coding, an outlier review, heterogeneity analysis, estimating the overall and subgroup effect sizes, and publication bias review were performed, using the R statistical program. The results showed that music intervention has statistical significance in reducing anxiety, presenting an overall effect size of -0.77 at a moderate level. Furthermore, there were influences from moderating variables, such as the music intervention used and the number of intervention sessions on the effect sizes. The results of the study provide practical information for music therapy practice aimed at anxiety reduction and aim to foster scholarly discussions for enhancing related evidence-based research.